Meiosis involves a complex succession of chromosomal events that result in the physical connection of homologous chromosomes. These events occur during a prolonged prophase period that precedes the two meiotic divisions. Connections between homologs are established during prophase and then ensure that maternal and paternal homologous chromosomes segregate to opposite poles later, during the first meiotic division. These connections, seen cytologically as “chiasmata”, result from the combined effects of reciprocal crossovers (COs) between non-sister chromatids of homologs and sister connections along the chromosome arms. Sister chromatid cohesion, mediated by ring-shaped cohesin complexes, is crucial for meiotic chromosomal events. The meiotic cohesin complex, formed in the presence of the meiosis-specific alpha-kleisin subunit Rec8, abundantly occupies the conjoined sister structural axes that form during prophase. Rec8 is required for axis formation and, thus, ensuing formation of synaptonemal complexes (SCs), which join the axes of homologs at mid-prophase. We study the detail process of chromosome dynamics during meiosis (Yeast and mice).